LY75/DEC-205 anticorps (PE)

N° du produit ABIN951226

Cet anticorps Souris Monoclonal détecte spécifiquement LY75/DEC-205 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour LY75/DEC-205 anticorps (PE) (ABIN951226)

Antigène: LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LY75/DEC-205 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: HD30

Détail du produit anti-LY75/DEC-205 anticorps (PE)

Specificité: This antibody detects CD205.

Réactivité croisée (Details): Species reactivity (tested):Human

Immunogène: Recombinant Fc-tagged human CD205

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE! This product is photosensitive and should be protected from light.

Stock: 4 °C

Détails sur LY75/DEC-205

Antigène: LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

Autre désignation: CD205 / DEC-205

Sujet: CD205, also known as DEC-205, is an endocytic receptor of macrophage mannose receptor family. This 205 kDa C-type lectin transmembrane protein mediates adsorptive uptake and its intracellular domain contains coated pit localization sequence and distal acidic motif, which is required for recycling beyond early endosomes through deeper MHC II+ late endosomes and lysosomes. This unique pathway of receptor-mediated uptake proves to be necessary for presentation of antigenic peptides at low doses of ligand. CD205 is responsible for uptake and processing of captured antigens for dendritic cells.Synonyms: C-type lectin domain family 13 member B, CLEC13B, DEC205, LY75, Lymphocyte antigen 75, gp200-MR6

ID gène: 100526664

NCBI Accession: NP_001185688

UniProt: O60449